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Optimal Attenuation of Experimental Autoimmune Encephalomyelitis by Intravenous Immunoglobulin Requires an Intact Interleukin-11 Receptor

BACKGROUND: Intravenous immunoglobulin (IVIg) has been used to treat a variety of autoimmune disorders including multiple sclerosis (MS); however its mechanism of action remains elusive. Recent work has shown that interleukin-11 (IL-11) mRNAs are upregulated by IVIg in MS patient T cells. Both IVIg...

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Detalles Bibliográficos
Autores principales: Figueiredo, Carlyn A., Drohomyrecky, Paulina C., McCarthy, Stephen D. S., Leontyev, Danila, Ma, Xue-Zhong, Branch, Donald R., Dunn, Shannon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117465/
https://www.ncbi.nlm.nih.gov/pubmed/25078447
http://dx.doi.org/10.1371/journal.pone.0101947