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Optimal Attenuation of Experimental Autoimmune Encephalomyelitis by Intravenous Immunoglobulin Requires an Intact Interleukin-11 Receptor
BACKGROUND: Intravenous immunoglobulin (IVIg) has been used to treat a variety of autoimmune disorders including multiple sclerosis (MS); however its mechanism of action remains elusive. Recent work has shown that interleukin-11 (IL-11) mRNAs are upregulated by IVIg in MS patient T cells. Both IVIg...
Autores principales: | Figueiredo, Carlyn A., Drohomyrecky, Paulina C., McCarthy, Stephen D. S., Leontyev, Danila, Ma, Xue-Zhong, Branch, Donald R., Dunn, Shannon E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117465/ https://www.ncbi.nlm.nih.gov/pubmed/25078447 http://dx.doi.org/10.1371/journal.pone.0101947 |
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