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Real-Time Monitoring of Protein Conformational Changes Using a Nano-Mechanical Sensor
Proteins can switch between different conformations in response to stimuli, such as pH or temperature variations, or to the binding of ligands. Such plasticity and its kinetics can have a crucial functional role, and their characterization has taken center stage in protein research. As an example, T...
Autores principales: | Alonso-Sarduy, Livan, De Los Rios, Paolo, Benedetti, Fabrizio, Vobornik, Dusan, Dietler, Giovanni, Kasas, Sandor, Longo, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117498/ https://www.ncbi.nlm.nih.gov/pubmed/25077809 http://dx.doi.org/10.1371/journal.pone.0103674 |
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