Human APOBEC3 Induced Mutation of Human Immunodeficiency Virus Type-1 Contributes to Adaptation and Evolution in Natural Infection

Human APOBEC3 proteins are cytidine deaminases that contribute broadly to innate immunity through the control of exogenous retrovirus replication and endogenous retroelement retrotransposition. As an intrinsic antiretroviral defense mechanism, APOBEC3 proteins induce extensive guanosine-to-adenosine...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Young, Lorenzo-Redondo, Ramon, Little, Susan J., Chung, Yoon-Seok, Phalora, Prabhjeet K., Maljkovic Berry, Irina, Archer, John, Penugonda, Sudhir, Fischer, Will, Richman, Douglas D., Bhattacharya, Tanmoy, Malim, Michael H., Wolinsky, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117599/
https://www.ncbi.nlm.nih.gov/pubmed/25080100
http://dx.doi.org/10.1371/journal.ppat.1004281

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