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Cytolethal Distending Toxins Require Components of the ER-Associated Degradation Pathway for Host Cell Entry

Intracellular acting protein exotoxins produced by bacteria and plants are important molecular determinants that drive numerous human diseases. A subset of these toxins, the cytolethal distending toxins (CDTs), are encoded by several Gram-negative pathogens and have been proposed to enhance virulenc...

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Detalles Bibliográficos
Autores principales: Eshraghi, Aria, Dixon, Shandee D., Tamilselvam, Batcha, Kim, Emily Jin-Kyung, Gargi, Amandeep, Kulik, Julia C., Damoiseaux, Robert, Blanke, Steven R., Bradley, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117610/
https://www.ncbi.nlm.nih.gov/pubmed/25078082
http://dx.doi.org/10.1371/journal.ppat.1004295