Plasmacytoid Dendritic Cells Suppress HIV-1 Replication but Contribute to HIV-1 Induced Immunopathogenesis in Humanized Mice

The role of plasmacytoid dendritic cells (pDC) in human immunodeficiency virus type 1 (HIV-1) infection and pathogenesis remains unclear. HIV-1 infection in the humanized mouse model leads to persistent HIV-1 infection and immunopathogenesis, including type I interferons (IFN-I) induction, immune-ac...

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Detalles Bibliográficos
Autores principales: Li, Guangming, Cheng, Menglan, Nunoya, Jun-ichi, Cheng, Liang, Guo, Haitao, Yu, Haisheng, Liu, Yong-jun, Su, Lishan, Zhang, Liguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117636/
https://www.ncbi.nlm.nih.gov/pubmed/25077616
http://dx.doi.org/10.1371/journal.ppat.1004291

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