Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1

We investigated the role of Toll-like receptor (TLR) 2 in maintaining the integrity of the airway epithelial barrier using the human bronchial epithelial cell line Calu-3. Activation of TLR2 by its ligands, Pam3CysSK4 and Peptidoglycan showed a concentration dependent increase in epithelial barrier...

Descripción completa

Detalles Bibliográficos
Autores principales: Ragupathy, Sakthikumar, Esmaeili, Farnaz, Paschoud, Serge, Sublet, Emmanuelle, Citi, Sandra, Borchard, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117686/
https://www.ncbi.nlm.nih.gov/pubmed/25101232
http://dx.doi.org/10.4161/tisb.29166

Ejemplares similares

Ejemplares similares