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Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix
The membrane-anchored collagenase membrane type 1 matrix metalloprotease (MT1-MMP) has been shown to play an essential role during epithelial tubulogenesis in 3D collagen matrices; however, its regulation during tubulogenesis is not understood. Here, we report that degradation of collagen in polariz...
Autores principales: | Weaver, Sarah A., Wolters, Brit, Ito, Noriko, Woskowicz, Anna M., Kaneko, Kazuyo, Shitomi, Yasuyuki, Seiki, Motoharu, Itoh, Yoshifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117704/ https://www.ncbi.nlm.nih.gov/pubmed/24463815 http://dx.doi.org/10.1242/jcs.135236 |
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