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RAMICS: trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA

The challenge presented by high-throughput sequencing necessitates the development of novel tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly to large genomes, rather than generating highly accurate alignments in coding re...

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Detalles Bibliográficos
Autores principales: Wright, Imogen A., Travers, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117746/
https://www.ncbi.nlm.nih.gov/pubmed/24861618
http://dx.doi.org/10.1093/nar/gku473