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RAMICS: trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA
The challenge presented by high-throughput sequencing necessitates the development of novel tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly to large genomes, rather than generating highly accurate alignments in coding re...
Autores principales: | Wright, Imogen A., Travers, Simon A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117746/ https://www.ncbi.nlm.nih.gov/pubmed/24861618 http://dx.doi.org/10.1093/nar/gku473 |
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