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The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage
Accurate replication of the genome requires the evolutionarily conserved minichromosome maintenance protein, Mcm10. Although the details of the precise role of Mcm10 in DNA replication are still debated, it interacts with the Mcm2-7 core helicase, the lagging strand polymerase, DNA polymerase-α and...
Autores principales: | Alver, Robert C., Zhang, Tianji, Josephrajan, Ajeetha, Fultz, Brandy L., Hendrix, Chance J., Das-Bradoo, Sapna, Bielinsky, Anja-Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117747/ https://www.ncbi.nlm.nih.gov/pubmed/24972833 http://dx.doi.org/10.1093/nar/gku479 |
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