Cargando…

The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems

We provide the first comprehensive analysis of any transcription factor family in Cryptosporidium, a basal-branching apicomplexan that is the second leading cause of infant diarrhea globally. AP2 domain-containing proteins have evolved to be the major regulatory family in the phylum to the exclusion...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oberstaller, Jenna, Pumpalova, Yoanna, Schieler, Ariel, Llinás, Manuel, Kissinger, Jessica C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117751/ https://www.ncbi.nlm.nih.gov/pubmed/24957599 http://dx.doi.org/10.1093/nar/gku500

Ejemplares similares

Cooperative binding of ApiAP2 transcription factors is crucial for the expression of virulence genes in Toxoplasma gondii
por: Lesage, Kevin M, et al.
Publicado: (2018)

Genome-wide landscape of ApiAP2 transcription factors reveals a heterochromatin-associated regulatory network during Plasmodium falciparum blood-stage development
por: Shang, Xiaomin, et al.
Publicado: (2022)

ApiAP2 Transcription Factors in Apicomplexan Parasites
por: Jeninga, Myriam D., et al.
Publicado: (2019)

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation
por: Dong, Wen, et al.
Publicado: (2012)

AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis
por: Lee, Jiyoon, et al.
Publicado: (2014)

TelAP1 links telomere complexes with developmental expression site silencing in African trypanosomes
por: Reis, Helena, et al.
Publicado: (2018)

Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK–ERK/AP-1 pathway
por: Chauhan, Santosh, et al.
Publicado: (2012)

Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation
por: McDade, Simon S., et al.
Publicado: (2012)

Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer
por: Moquet-Torcy, Gabriel, et al.
Publicado: (2014)

Sequence-specific dynamics of DNA response elements and their flanking sites regulate the recognition by AP-1 transcription factors
por: Hörberg, Johanna, et al.
Publicado: (2021)

Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis
por: Radke, Joshua B., et al.
Publicado: (2018)

Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta
por: Hong, Samuel, et al.
Publicado: (2017)

The ancillary N-terminal region of the yeast AP-1 transcription factor Yap8 contributes to its DNA binding specificity
por: Maciaszczyk-Dziubinska, Ewa, et al.
Publicado: (2020)

The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells
por: Pramanik, Suravi, et al.
Publicado: (2022)

The ApiAP2 factor PfAP2-HC is an integral component of heterochromatin in the malaria parasite Plasmodium falciparum
por: Carrington, Eilidh, et al.
Publicado: (2021)

Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites
por: Russell, Timothy James, et al.
Publicado: (2022)

RbAp46/48(LIN-53) and HAT-1 are required for initial CENP-A(HCP-3) deposition and de novo holocentromere formation on artificial chromosomes in Caenorhabditis elegans embryos
por: Lin, Zhongyang, et al.
Publicado: (2021)

Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite
por: Campbell, Tracey L., et al.
Publicado: (2010)

Oncogenic ERRB2 signals through the AP-1 transcription factor to control mesenchymal-like properties of oesophageal adenocarcinoma
por: Ogden, Samuel, et al.
Publicado: (2023)

ApiAP2 Factors as Candidate Regulators of Stochastic Commitment to Merozoite Production in Theileria annulata
por: Pieszko, Marta, et al.
Publicado: (2015)

Genome-wide upstream motif analysis of Cryptosporidium parvum genes clustered by expression profile
por: Oberstaller, Jenna, et al.
Publicado: (2013)

A single-nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor alters the development of host immunity
por: Akkaya, Munir, et al.
Publicado: (2020)

An ApiAP2 member regulates expression of clonally variant genes of the human malaria parasite Plasmodium falciparum
por: Martins, Rafael M., et al.
Publicado: (2017)

A Major Role for the Plasmodium falciparum ApiAP2 Protein PfSIP2 in Chromosome End Biology
por: Flueck, Christian, et al.
Publicado: (2010)

The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex
por: Ji, Zongling, et al.
Publicado: (2014)

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX
por: Alqarni, Saad S. M., et al.
Publicado: (2014)

Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation
por: Khamis, Hadeel, et al.
Publicado: (2021)

A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle
por: Modrzynska, Katarzyna, et al.
Publicado: (2017)

Regulation of chromatin folding by conformational variations of nucleosome linker DNA
por: Buckwalter, Jenna M., et al.
Publicado: (2017)

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development
por: Zhang, Cui, et al.
Publicado: (2017)

H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization
por: Bönisch, Clemens, et al.
Publicado: (2012)

Insights into Association of the NuRD Complex with FOG-1 from the Crystal Structure of an RbAp48·FOG-1 Complex
por: Lejon, Sara, et al.
Publicado: (2011)

Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers
por: Mariani, J., et al.
Publicado: (2012)

CK2 promotes jasmonic acid signaling response by phosphorylating MYC2 in Arabidopsis
por: Zhu, Jiang, et al.
Publicado: (2022)

Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
por: Carullo, Nancy V N, et al.
Publicado: (2020)

E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes
por: Laresgoiti, Usua, et al.
Publicado: (2013)

Three classes of response elements for human PRC2 and MLL1/2–Trithorax complexes
por: Du, Junqing, et al.
Publicado: (2018)

Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays
por: Lam, Kathy N., et al.
Publicado: (2011)

A new, highly conserved domain in Swi2/Snf2 is required for SWI/SNF remodeling
por: Sen, Payel, et al.
Publicado: (2011)

Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination
por: Wüst, Hannah M, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0roeth3bnkh395vbg8elilbsn0