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Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer
Clustered regularly interspaced short palindromic repeats (CRISPR), in combination with CRISPR associated (cas) genes, constitute CRISPR-Cas bacterial adaptive immune systems. To generate immunity, these systems acquire short sequences of nucleic acids from foreign invaders and incorporate these int...
Autores principales: | Richter, Corinna, Dy, Ron L., McKenzie, Rebecca E., Watson, Bridget N.J., Taylor, Corinda, Chang, James T., McNeil, Matthew B., Staals, Raymond H.J., Fineran, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117759/ https://www.ncbi.nlm.nih.gov/pubmed/24990370 http://dx.doi.org/10.1093/nar/gku527 |
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