Cargando…

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis

The proliferating cell nuclear antigen (PCNA) protein serves as a molecular platform recruiting and coordinating the activity of factors involved in multiple deoxyribonucleic acid (DNA) transactions. To avoid dangerous genome instability, it is necessary to prevent excessive retention of PCNA on chr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cazzalini, Ornella, Sommatis, Sabrina, Tillhon, Micol, Dutto, Ilaria, Bachi, Angela, Rapp, Alexander, Nardo, Tiziana, Scovassi, A. Ivana, Necchi, Daniela, Cardoso, M. Cristina, Stivala, Lucia A., Prosperi, Ennio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117764/ https://www.ncbi.nlm.nih.gov/pubmed/24939902 http://dx.doi.org/10.1093/nar/gku533

Ejemplares similares

Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair
por: Cazzalini, Ornella, et al.
Publicado: (2008)

p21(CDKN1A) Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates
por: Dutto, Ilaria, et al.
Publicado: (2016)

Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG
por: Scalera, Claudia, et al.
Publicado: (2021)

Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway
por: Masuda, Yuji, et al.
Publicado: (2018)

Role of SUMO modification of human PCNA at stalled replication fork
por: Gali, Himabindu, et al.
Publicado: (2012)

PCNA promotes processive DNA end resection by Exo1
por: Chen, Xiaoqing, et al.
Publicado: (2013)

p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair
por: Wang, Qi-En, et al.
Publicado: (2013)

FANCM interacts with PCNA to promote replication traverse of DNA interstrand crosslinks
por: Rohleder, Florian, et al.
Publicado: (2016)

PCNA tool belts and polymerase bridges form during translesion synthesis
por: Boehm, Elizabeth M., et al.
Publicado: (2016)

Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation
por: Guarino, Estrella, et al.
Publicado: (2011)

Effects of chain length and geometry on the activation of DNA damage bypass by polyubiquitylated PCNA
por: Takahashi, Diane T, et al.
Publicado: (2020)

The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA
por: Saugar, Irene, et al.
Publicado: (2012)

PCNA directs type 2 RNase H activity on DNA replication and repair substrates
por: Bubeck, Doryen, et al.
Publicado: (2011)

PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms
por: Mortusewicz, Oliver, et al.
Publicado: (2011)

Constitutive fusion of ubiquitin to PCNA provides DNA damage tolerance independent of translesion polymerase activities
por: Pastushok, Landon, et al.
Publicado: (2010)

Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex
por: Paul Solomon Devakumar, Lovely Jael, et al.
Publicado: (2019)

The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis
por: Burkovics, Peter, et al.
Publicado: (2016)

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage
por: Wit, Niek, et al.
Publicado: (2015)

Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner
por: Becker, Jordan R, et al.
Publicado: (2018)

Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination
por: Park, Su Hyung, et al.
Publicado: (2023)

DNA-damage tolerance mediated by PCNA•Ub fusions in human cells is dependent on Rev1 but not Polη
por: Qin, Zhoushuai, et al.
Publicado: (2013)

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance
por: Juhasz, Szilvia, et al.
Publicado: (2012)

ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork
por: Kim, Sangin, et al.
Publicado: (2020)

A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA
por: Parker, Joanne L., et al.
Publicado: (2012)

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells
por: Bacquin, Agathe, et al.
Publicado: (2013)

Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases
por: Masuda, Yuji, et al.
Publicado: (2015)

A structure–function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance
por: Shemesh, Keren, et al.
Publicado: (2017)

PCNA monoubiquitylation and DNA polymerase η ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae
por: van der Kemp, Patricia Auffret, et al.
Publicado: (2009)

A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks
por: Durando, Michael, et al.
Publicado: (2013)

Physical and functional interplay between PCNA DNA clamp and Mre11–Rad50 complex from the archaeon Pyrococcus furiosus
por: Hogrel, Gaëlle, et al.
Publicado: (2018)

Role of PCNA-dependent stimulation of 3′-phosphodiesterase and 3′–5′ exonuclease activities of human Ape2 in repair of oxidative DNA damage
por: Burkovics, Peter, et al.
Publicado: (2009)

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp
por: Fujisawa, Ryo, et al.
Publicado: (2017)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

Base excision repair of 8-oxoG in dinucleosomes
por: Menoni, Hervé, et al.
Publicado: (2012)

Kinetics of endogenous mouse FEN1 in base excision repair
por: Kleppa, Liv, et al.
Publicado: (2012)

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence
por: Allgayer, Julia, et al.
Publicado: (2013)

The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
por: Šebera, Jakub, et al.
Publicado: (2017)

p53 coordinates base excision repair to prevent genomic instability
por: Poletto, Mattia, et al.
Publicado: (2016)

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts
por: Çağlayan, Melike, et al.
Publicado: (2017)

Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair
por: Fu, Iwen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4bm5a7vrhh82dcp9r8l5parknq