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Structural studies of CNG repeats

CNG repeats (where N denotes one of the four natural nucleotides) are abundant in the human genome. Their tendency to undergo expansion can lead to hereditary diseases known as TREDs (trinucleotide repeat expansion disorders). The toxic factor can be protein, if the abnormal gene is expressed, or th...

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Detalles Bibliográficos
Autores principales: Kiliszek, Agnieszka, Rypniewski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117766/
https://www.ncbi.nlm.nih.gov/pubmed/24939898
http://dx.doi.org/10.1093/nar/gku536

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