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Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes
During eukaryotic ribosome biogenesis, members of the conserved atypical serine/threonine protein kinase family, the RIO kinases (Rio1, Rio2 and Rio3) function in small ribosomal subunit biogenesis. Structural analysis of Rio2 indicated a role as a conformation-sensing ATPase rather than a kinase to...
Autores principales: | Ferreira-Cerca, Sébastien, Kiburu, Irene, Thomson, Emma, LaRonde, Nicole, Hurt, Ed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117770/ https://www.ncbi.nlm.nih.gov/pubmed/24948609 http://dx.doi.org/10.1093/nar/gku542 |
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