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TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation

The discovery of hydroxymethyl-, formyl- and carboxylcytosine, generated through oxidation of methylcytosine by TET dioxygenases, raised the question how these modifications contribute to epigenetic regulation. As they are subjected to complex regulation in vivo, we dissected links to gene expressio...

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Detalles Bibliográficos
Autores principales:	Müller, Udo, Bauer, Christina, Siegl, Michael, Rottach, Andrea, Leonhardt, Heinrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117777/ https://www.ncbi.nlm.nih.gov/pubmed/24948610 http://dx.doi.org/10.1093/nar/gku552

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