Catalysis-dependent stabilization of Bre1 fine-tunes histone H2B ubiquitylation to regulate gene transcription

Monoubiquitylation of histone H2B on Lys123 (H2BK123ub1) plays a multifaceted role in diverse DNA-templated processes, yet the mechanistic details by which this modification is regulated are not fully elucidated. Here we show in yeast that H2BK123ub1 is regulated in part through the protein stabilit...

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Detalles Bibliográficos
Autores principales: Wozniak, Glenn G., Strahl, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117940/
https://www.ncbi.nlm.nih.gov/pubmed/25085417
http://dx.doi.org/10.1101/gad.243121.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117940/
https://www.ncbi.nlm.nih.gov/pubmed/25085417
http://dx.doi.org/10.1101/gad.243121.114

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