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Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity
ABSTRACT: Mitochondrial ferritin is a functional ferritin that localizes in the mitochondria. It is expressed in the testis, heart, brain, and cells with active respiratory activity. Its overexpression in cultured cells protected against oxidative damage and reduced cytosolic iron availability. Howe...
Autores principales: | Maccarinelli, Federica, Gammella, Elena, Asperti, Michela, Regoni, Maria, Biasiotto, Giorgio, Turco, Emilia, Altruda, Fiorella, Lonardi, Silvia, Cornaghi, Laura, Donetti, Elena, Recalcati, Stefania, Poli, Maura, Finazzi, Dario, Arosio, Paolo, Cairo, Gaetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118045/ https://www.ncbi.nlm.nih.gov/pubmed/24728422 http://dx.doi.org/10.1007/s00109-014-1147-0 |
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