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Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models
Keratinocyte growth factor (KGF) is a paracrine-acting epithelial mitogen produced by cells of mesenchymal origin, that plays an important role in protecting and repairing epithelial tissues. Pre-clinical data initially demonstrated that a recombinant truncated KGF (palifermin) could reduce gastroin...
Autores principales: | Finch, Paul W, Mark Cross, Lawrence J, McAuley, Daniel F, Farrell, Catherine L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118166/ https://www.ncbi.nlm.nih.gov/pubmed/24151975 http://dx.doi.org/10.1111/jcmm.12091 |
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