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Lipid-laden partially-activated plasmacytoid and CD4(−)CD8α(+) dendritic cells accumulate in tissues in elderly mice

BACKGROUND: Aging is associated with a decline in lymphocyte function however, little is known about dendritic cell (DC) subsets and aging. Aging is also associated with increasing circulating lipid levels and intracellular lipid accumulation modulates DC function. Whether age-associated increases i...

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Detalles Bibliográficos
Autores principales:	Gardner, Joanne K, Mamotte, Cyril DS, McGonigle, Terrence, Dye, Danielle E, Jackaman, Connie, Nelson, Delia J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118209/ https://www.ncbi.nlm.nih.gov/pubmed/25089147 http://dx.doi.org/10.1186/1742-4933-11-11

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