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Validation of a Janus role of methotrexate-based PEGylated chitosan nanoparticles in vitro

Recently, methotrexate (MTX) has been used to target to folate (FA) receptor-overexpressing cancer cells for targeted drug delivery. However, the systematic evaluation of MTX as a Janus-like agent has not been reported before. Here, we explored the validity of using MTX playing an early-phase cancer...

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Detalles Bibliográficos
Autores principales:	Luo, Fanghong, Li, Yang, Jia, Mengmeng, Cui, Fei, Wu, Hongjie, Yu, Fei, Lin, Jinyan, Yang, Xiangrui, Hou, Zhenqing, Zhang, Qiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2014
Materias:	Nano Express
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118220/ https://www.ncbi.nlm.nih.gov/pubmed/25114653 http://dx.doi.org/10.1186/1556-276X-9-363

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