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Akt- and Erk-mediated regulation of proliferation and differentiation during PDGFRβ-induced MSC self-renewal

Understanding the mechanisms that direct mesenchymal stem cell (MSC) self-renewal fate decisions is a key to most tissue regenerative approaches. The aim of this study here was to investigate the mechanisms of action of platelet-derived growth factor receptor β (PDGFRβ) signalling on MSC proliferati...

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Detalles Bibliográficos
Autores principales: Gharibi, Borzo, Ghuman, Mandeep S, Hughes, Francis J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118247/
https://www.ncbi.nlm.nih.gov/pubmed/22805337
http://dx.doi.org/10.1111/j.1582-4934.2012.01602.x

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