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Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118728/ https://www.ncbi.nlm.nih.gov/pubmed/25114722 http://dx.doi.org/10.3332/ecancer.2014.450 |
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author | Kuriakose, Santhosh Umadevi, N Mathew, Sheela Supriya, NK Aravindan, KP Smitha, DS Amritha Malini, G |
author_facet | Kuriakose, Santhosh Umadevi, N Mathew, Sheela Supriya, NK Aravindan, KP Smitha, DS Amritha Malini, G |
author_sort | Kuriakose, Santhosh |
collection | PubMed |
description | Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour. |
format | Online Article Text |
id | pubmed-4118728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-41187282014-08-11 Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature Kuriakose, Santhosh Umadevi, N Mathew, Sheela Supriya, NK Aravindan, KP Smitha, DS Amritha Malini, G Ecancermedicalscience Case Report Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour. Cancer Intelligence 2014-07-31 /pmc/articles/PMC4118728/ /pubmed/25114722 http://dx.doi.org/10.3332/ecancer.2014.450 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kuriakose, Santhosh Umadevi, N Mathew, Sheela Supriya, NK Aravindan, KP Smitha, DS Amritha Malini, G Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature |
title | Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature |
title_full | Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature |
title_fullStr | Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature |
title_full_unstemmed | Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature |
title_short | Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature |
title_sort | neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic siadh—a rare case report and brief review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118728/ https://www.ncbi.nlm.nih.gov/pubmed/25114722 http://dx.doi.org/10.3332/ecancer.2014.450 |
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