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Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature

Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to...

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Autores principales: Kuriakose, Santhosh, Umadevi, N, Mathew, Sheela, Supriya, NK, Aravindan, KP, Smitha, DS, Amritha Malini, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118728/
https://www.ncbi.nlm.nih.gov/pubmed/25114722
http://dx.doi.org/10.3332/ecancer.2014.450
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author Kuriakose, Santhosh
Umadevi, N
Mathew, Sheela
Supriya, NK
Aravindan, KP
Smitha, DS
Amritha Malini, G
author_facet Kuriakose, Santhosh
Umadevi, N
Mathew, Sheela
Supriya, NK
Aravindan, KP
Smitha, DS
Amritha Malini, G
author_sort Kuriakose, Santhosh
collection PubMed
description Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour.
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spelling pubmed-41187282014-08-11 Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature Kuriakose, Santhosh Umadevi, N Mathew, Sheela Supriya, NK Aravindan, KP Smitha, DS Amritha Malini, G Ecancermedicalscience Case Report Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour. Cancer Intelligence 2014-07-31 /pmc/articles/PMC4118728/ /pubmed/25114722 http://dx.doi.org/10.3332/ecancer.2014.450 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kuriakose, Santhosh
Umadevi, N
Mathew, Sheela
Supriya, NK
Aravindan, KP
Smitha, DS
Amritha Malini, G
Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
title Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
title_full Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
title_fullStr Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
title_full_unstemmed Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
title_short Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature
title_sort neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic siadh—a rare case report and brief review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118728/
https://www.ncbi.nlm.nih.gov/pubmed/25114722
http://dx.doi.org/10.3332/ecancer.2014.450
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