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Interaction of serum amyloid P component with hexanoyl bis(d-proline) (CPHPC)

Under physiological conditions, the pentameric human plasma protein serum amyloid P component (SAP) binds hexanoyl bis(d-proline) (R-1-{6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl}pyrrolidine-2-carboxylic acid; CPHPC) through its d-proline head groups in a calcium-dependent interaction. Cooperati...

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Detalles Bibliográficos
Autores principales: Kolstoe, Simon E., Jenvey, Michelle C., Purvis, Alan, Light, Mark E., Thompson, Darren, Hughes, Peter, Pepys, Mark B., Wood, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118831/
https://www.ncbi.nlm.nih.gov/pubmed/25084341
http://dx.doi.org/10.1107/S1399004714013455

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