Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells

Timely characterization of a cancer's evolution is required to predict treatment efficacy and to detect resistance early. High content analysis of single Circulating Tumor Cells (CTCs) enables sequential characterization of genotypic, morphometric and protein expression alterations in real time...

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Detalles Bibliográficos
Autores principales: Dago, Angel E., Stepansky, Asya, Carlsson, Anders, Luttgen, Madelyn, Kendall, Jude, Baslan, Timour, Kolatkar, Anand, Wigler, Michael, Bethel, Kelly, Gross, Mitchell E., Hicks, James, Kuhn, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118839/
https://www.ncbi.nlm.nih.gov/pubmed/25084170
http://dx.doi.org/10.1371/journal.pone.0101777

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