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EZH2 Is Associated with Malignant Behavior in Pancreatic IPMN via p27(Kip1) Downregulation

BACKGROUND: The epigenetic mechanism of tumorigenesis in pancreatic intraductal papillary mucinous neoplasm (IPMN) remains largely unknown. The aim of this study is to examine the role of enhancer of zeste homologue 2 (EZH2) alteration in pancreatic IPMN progression. METHODS: Fifty-four surgically r...

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Detalles Bibliográficos
Autores principales:	Kuroki, Hideyuki, Hayashi, Hiromitsu, Okabe, Hirohisa, Hashimoto, Daisuke, Takamori, Hiroshi, Nakahara, Osamu, Nakagawa, Shigeki, Fukushima, Yukiko, Chikamoto, Akira, Beppu, Toru, Hirota, Masahiko, Iyama, Ken-ichi, Baba, Hideo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118850/ https://www.ncbi.nlm.nih.gov/pubmed/25084021 http://dx.doi.org/10.1371/journal.pone.0100904

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