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Identification of ALK Gene Alterations in Urothelial Carcinoma

BACKGROUND: Anaplastic lymphoma kinase (ALK) genomic alterations have emerged as a potent predictor of benefit from treatment with ALK inhibitors in several cancers. Currently, there is no information about ALK gene alterations in urothelial carcinoma (UC) and its correlation with clinical or pathol...

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Detalles Bibliográficos
Autores principales: Bellmunt, Joaquim, Selvarajah, Shamini, Rodig, Scott, Salido, Marta, de Muga, Silvia, Costa, Irmgard, Bellosillo, Beatriz, Werner, Lillian, Mullane, Stephanie, Fay, André P., O'Brien, Robert, Barretina, Jordi, Minoche, André E., Signoretti, Sabina, Montagut, Clara, Himmelbauer, Heinz, Berman, David M., Kantoff, Philip, Choueiri, Toni K., Rosenberg, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118868/
https://www.ncbi.nlm.nih.gov/pubmed/25083769
http://dx.doi.org/10.1371/journal.pone.0103325