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Myotonia Congenita-Associated Mutations in Chloride Channel-1 Affect Zebrafish Body Wave Swimming Kinematics
Myotonia congenita is a human muscle disorder caused by mutations in CLCN1, which encodes human chloride channel 1 (CLCN1). Zebrafish is becoming an increasingly useful model for human diseases, including muscle disorders. In this study, we generated transgenic zebrafish expressing, under the contro...
Autores principales: | Cheng, Wei, Tian, Jing, Burgunder, Jean-Marc, Hunziker, Walter, Eng, How-Lung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118878/ https://www.ncbi.nlm.nih.gov/pubmed/25083883 http://dx.doi.org/10.1371/journal.pone.0103445 |
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