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GMEnzy: A Genetically Modified Enzybiotic Database

GMEs are genetically modified enzybiotics created through molecular engineering approaches to deal with the increasing problem of antibiotic resistance prevalence. We present a fully manually curated database, GMEnzy, which focuses on GMEs and their design strategies, production and purification met...

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Detalles Bibliográficos
Autores principales: Wu, Hongyu, Huang, Jinjiang, Lu, Hairong, Li, Guodong, Huang, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118892/
https://www.ncbi.nlm.nih.gov/pubmed/25084271
http://dx.doi.org/10.1371/journal.pone.0103687
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author Wu, Hongyu
Huang, Jinjiang
Lu, Hairong
Li, Guodong
Huang, Qingshan
author_facet Wu, Hongyu
Huang, Jinjiang
Lu, Hairong
Li, Guodong
Huang, Qingshan
author_sort Wu, Hongyu
collection PubMed
description GMEs are genetically modified enzybiotics created through molecular engineering approaches to deal with the increasing problem of antibiotic resistance prevalence. We present a fully manually curated database, GMEnzy, which focuses on GMEs and their design strategies, production and purification methods, and biological activity data. GMEnzy collects and integrates all available GMEs and their related information into one web based database. Currently GMEnzy holds 186 GMEs from published literature. The GMEnzy interface is easy to use, and allows users to rapidly retrieve data according to desired search criteria. GMEnzy’s construction will increase the efficiency and convenience of improving these bioactive proteins for specific requirements, and will expand the arsenal available for researches to control drug-resistant pathogens. This database will prove valuable for researchers interested in genetically modified enzybiotics studies. GMEnzy is freely available on the Web at http://biotechlab.fudan.edu.cn/database/gmenzy/.
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spelling pubmed-41188922014-08-04 GMEnzy: A Genetically Modified Enzybiotic Database Wu, Hongyu Huang, Jinjiang Lu, Hairong Li, Guodong Huang, Qingshan PLoS One Research Article GMEs are genetically modified enzybiotics created through molecular engineering approaches to deal with the increasing problem of antibiotic resistance prevalence. We present a fully manually curated database, GMEnzy, which focuses on GMEs and their design strategies, production and purification methods, and biological activity data. GMEnzy collects and integrates all available GMEs and their related information into one web based database. Currently GMEnzy holds 186 GMEs from published literature. The GMEnzy interface is easy to use, and allows users to rapidly retrieve data according to desired search criteria. GMEnzy’s construction will increase the efficiency and convenience of improving these bioactive proteins for specific requirements, and will expand the arsenal available for researches to control drug-resistant pathogens. This database will prove valuable for researchers interested in genetically modified enzybiotics studies. GMEnzy is freely available on the Web at http://biotechlab.fudan.edu.cn/database/gmenzy/. Public Library of Science 2014-08-01 /pmc/articles/PMC4118892/ /pubmed/25084271 http://dx.doi.org/10.1371/journal.pone.0103687 Text en © 2014 Wu et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wu, Hongyu
Huang, Jinjiang
Lu, Hairong
Li, Guodong
Huang, Qingshan
GMEnzy: A Genetically Modified Enzybiotic Database
title GMEnzy: A Genetically Modified Enzybiotic Database
title_full GMEnzy: A Genetically Modified Enzybiotic Database
title_fullStr GMEnzy: A Genetically Modified Enzybiotic Database
title_full_unstemmed GMEnzy: A Genetically Modified Enzybiotic Database
title_short GMEnzy: A Genetically Modified Enzybiotic Database
title_sort gmenzy: a genetically modified enzybiotic database
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118892/
https://www.ncbi.nlm.nih.gov/pubmed/25084271
http://dx.doi.org/10.1371/journal.pone.0103687
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