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TRIpartite Motif 21 (TRIM21) Differentially Regulates the Stability of Interferon Regulatory Factor 5 (IRF5) Isoforms

IRF5 is a member of the Interferon Regulatory Factor (IRF) family of transcription factors activated downstream of the Toll-Like receptors (TLRs). Polymorphisms in IRF5 have been shown to be associated with the autoimmune disease Systemic Lupus Erythematosus (SLE) and other autoimmune conditions, su...

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Detalles Bibliográficos
Autores principales:	Lazzari, Elisa, Korczeniewska, Justyna, Ní Gabhann, Joan, Smith, Siobhán, Barnes, Betsy J., Jefferies, Caroline A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118895/ https://www.ncbi.nlm.nih.gov/pubmed/25084355 http://dx.doi.org/10.1371/journal.pone.0103609

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