Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells

Fifteen percent of tumors utilize recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. The mechanisms underlying ALT are unclear but involve several proteins involved in homologous recombination including the BLM helicase, mutated in Bloom's syndrome, and the BR...

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Detalles Bibliográficos
Autores principales: Acharya, Samir, Kaul, Zeenia, Gocha, April Sandy, Martinez, Alaina R., Harris, Julia, Parvin, Jeffrey D., Groden, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118958/
https://www.ncbi.nlm.nih.gov/pubmed/25084169
http://dx.doi.org/10.1371/journal.pone.0103819

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