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Histone Deacetylase Inhibitor Valproic Acid Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells
In this study, we aimed to elucidate the effects and mechanism of action of valproic acid on hepatic differentiation from human induced pluripotent stem cell-derived hepatic progenitor cells. Human induced pluripotent stem cells were differentiated into endodermal cells in the presence of activin A...
Autores principales: | Kondo, Yuki, Iwao, Takahiro, Yoshihashi, Sachimi, Mimori, Kayo, Ogihara, Ruri, Nagata, Kiyoshi, Kurose, Kouichi, Saito, Masayoshi, Niwa, Takuro, Suzuki, Takayoshi, Miyata, Naoki, Ohmori, Shigeru, Nakamura, Katsunori, Matsunaga, Tamihide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119015/ https://www.ncbi.nlm.nih.gov/pubmed/25084468 http://dx.doi.org/10.1371/journal.pone.0104010 |
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