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Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice

BACKGROUND: Therapeutic idiotypic (Id) vaccination is an experimental treatment for selected B cell malignancies. A broader use of Id-based vaccination, however, is hampered by the complexity and costs due to the individualized production of protein vaccines. These limitations may be overcome by tar...

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Detalles Bibliográficos
Autores principales: Ruffini, Pier Adelchi, Os, Audun, Dolcetti, Riccardo, Tjønnfjord, Geir E, Munthe, Ludvig A, Bogen, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119056/
https://www.ncbi.nlm.nih.gov/pubmed/25059102
http://dx.doi.org/10.1186/1479-5876-12-207