Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis

The short allelic variant of the serotonin transporter (5-HTT) promoter-linked polymorphic region (5-HTTLPR) has been associated with the etiology of major depression by interaction with early life stress (ELS). Furthermore, 5-HTTLPR has been associated with abnormal functioning of the stress-respon...

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Detalles Bibliográficos
Autores principales: van der Doelen, R H A, Deschamps, W, D'Annibale, C, Peeters, D, Wevers, R A, Zelena, D, Homberg, J R, Kozicz, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119224/
https://www.ncbi.nlm.nih.gov/pubmed/25004389
http://dx.doi.org/10.1038/tp.2014.57

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