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Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases

Objectives: We are presenting our experience collected from a series of 109 cases with SCC of the lower lip focusing on clinical features of patients and surgical approach. Study Design: We retrospectively analyzed medical records of patients diagnosed with Squamous Cell Carcinoma (SCC) of the lower...

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Autores principales: Rena, Wenhao, Lia, Yin, Liua, Changyang, Qianga, Cui, Zhang, Linmei, Gaoa, Ling, Wangb, Zhi, Zhia, Keqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119317/
https://www.ncbi.nlm.nih.gov/pubmed/24608205
http://dx.doi.org/10.4317/medoral.19595
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author Rena, Wenhao
Lia, Yin
Liua, Changyang
Qianga, Cui
Zhang, Linmei
Gaoa, Ling
Wangb, Zhi
Zhia, Keqian
author_facet Rena, Wenhao
Lia, Yin
Liua, Changyang
Qianga, Cui
Zhang, Linmei
Gaoa, Ling
Wangb, Zhi
Zhia, Keqian
author_sort Rena, Wenhao
collection PubMed
description Objectives: We are presenting our experience collected from a series of 109 cases with SCC of the lower lip focusing on clinical features of patients and surgical approach. Study Design: We retrospectively analyzed medical records of patients diagnosed with Squamous Cell Carcinoma (SCC) of the lower lip at the Oral and Maxillofacial surgery at Xi’an Jiaotong University during a period between 1999 and 2008. Results: A total of 109 patients with lip cancer were included in the study. When no frozen-section test was performed, the neoplasia was removed with a margin of at least 6 mm. Different surgical techniques were used for lip reconstruction after tumor excision. Neck dissection was performed in all patients with clinically palpable lymph nodes. Median follow-up was 38 months. During follow-up, recurrence occurred in 5 patients, 3 patients developed neck metastases, distant metastases developed in 1 patient. Five patients died during observation period. Conclusions: The patient-related and defect-related issues must be taken into consideration during reconstruction for surgical defect. For N0 patients, we recommend wait-and-see policy. Early detection, careful follow-up and prompt neck is essential for the successful treatment. Key words:Lip cancer, surgical management, reconstruction.
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spelling pubmed-41193172014-08-14 Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases Rena, Wenhao Lia, Yin Liua, Changyang Qianga, Cui Zhang, Linmei Gaoa, Ling Wangb, Zhi Zhia, Keqian Med Oral Patol Oral Cir Bucal Research Objectives: We are presenting our experience collected from a series of 109 cases with SCC of the lower lip focusing on clinical features of patients and surgical approach. Study Design: We retrospectively analyzed medical records of patients diagnosed with Squamous Cell Carcinoma (SCC) of the lower lip at the Oral and Maxillofacial surgery at Xi’an Jiaotong University during a period between 1999 and 2008. Results: A total of 109 patients with lip cancer were included in the study. When no frozen-section test was performed, the neoplasia was removed with a margin of at least 6 mm. Different surgical techniques were used for lip reconstruction after tumor excision. Neck dissection was performed in all patients with clinically palpable lymph nodes. Median follow-up was 38 months. During follow-up, recurrence occurred in 5 patients, 3 patients developed neck metastases, distant metastases developed in 1 patient. Five patients died during observation period. Conclusions: The patient-related and defect-related issues must be taken into consideration during reconstruction for surgical defect. For N0 patients, we recommend wait-and-see policy. Early detection, careful follow-up and prompt neck is essential for the successful treatment. Key words:Lip cancer, surgical management, reconstruction. Medicina Oral S.L. 2014-07 2014-03-08 /pmc/articles/PMC4119317/ /pubmed/24608205 http://dx.doi.org/10.4317/medoral.19595 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Rena, Wenhao
Lia, Yin
Liua, Changyang
Qianga, Cui
Zhang, Linmei
Gaoa, Ling
Wangb, Zhi
Zhia, Keqian
Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases
title Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases
title_full Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases
title_fullStr Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases
title_full_unstemmed Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases
title_short Surgical management of Squamous Cell Carcinoma of the lower lip: An experience of 109 cases
title_sort surgical management of squamous cell carcinoma of the lower lip: an experience of 109 cases
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119317/
https://www.ncbi.nlm.nih.gov/pubmed/24608205
http://dx.doi.org/10.4317/medoral.19595
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