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Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap

Objectives: Mandibular resection for oral cancer is often necessary to achieve an adequate margin of tumor clearance. Mandibular resection has been associated with a poor health-related quality of life (HRQOL), particularly before free fibula flap to reconstruct the defect. The aim of this study was...

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Autores principales: Yang, Wenli, Zhao, Sanjun, Liu, Fei, Sun, Minglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119320/
https://www.ncbi.nlm.nih.gov/pubmed/24608209
http://dx.doi.org/10.4317/medoral.19399
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author Yang, Wenli
Zhao, Sanjun
Liu, Fei
Sun, Minglei
author_facet Yang, Wenli
Zhao, Sanjun
Liu, Fei
Sun, Minglei
author_sort Yang, Wenli
collection PubMed
description Objectives: Mandibular resection for oral cancer is often necessary to achieve an adequate margin of tumor clearance. Mandibular resection has been associated with a poor health-related quality of life (HRQOL), particularly before free fibula flap to reconstruct the defect. The aim of this study was to evaluate health-related quality of life in patients who have had mandibular resections of oral cancer and reconstruction with free fibula flap. Study Designs: There were 115 consecutive patients between 2008 and 2011 who were treated by primary surgery for oral squamous cell carcinoma, 34 patients had a mandibular resection. HRQOL was assessed by means of the 14-item Oral Health Impact Profile (OHIP-14) and University of Washington Quality of Life (UW-QOL) questionnaires after 12 months postoperatively. Results: In the UW-QOL the best-scoring domain was mood, whereas the lowest scores were for chewing and saliva. In the OHIP-14 the lowest-scoring domain was social disability, followed by handicap, and psychological disability. Conclusions: Mandible reconstruction with free fibula flap would have significantly influenced on patients’quality of life and oral functions. The socio-cultural data show a fairly low level of education for the majority of patients. Key words:Health-related quality of life, free fibula flap, mandibulectomy, UW-QOL, OHIP-14.
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spelling pubmed-41193202014-08-14 Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap Yang, Wenli Zhao, Sanjun Liu, Fei Sun, Minglei Med Oral Patol Oral Cir Bucal Research Objectives: Mandibular resection for oral cancer is often necessary to achieve an adequate margin of tumor clearance. Mandibular resection has been associated with a poor health-related quality of life (HRQOL), particularly before free fibula flap to reconstruct the defect. The aim of this study was to evaluate health-related quality of life in patients who have had mandibular resections of oral cancer and reconstruction with free fibula flap. Study Designs: There were 115 consecutive patients between 2008 and 2011 who were treated by primary surgery for oral squamous cell carcinoma, 34 patients had a mandibular resection. HRQOL was assessed by means of the 14-item Oral Health Impact Profile (OHIP-14) and University of Washington Quality of Life (UW-QOL) questionnaires after 12 months postoperatively. Results: In the UW-QOL the best-scoring domain was mood, whereas the lowest scores were for chewing and saliva. In the OHIP-14 the lowest-scoring domain was social disability, followed by handicap, and psychological disability. Conclusions: Mandible reconstruction with free fibula flap would have significantly influenced on patients’quality of life and oral functions. The socio-cultural data show a fairly low level of education for the majority of patients. Key words:Health-related quality of life, free fibula flap, mandibulectomy, UW-QOL, OHIP-14. Medicina Oral S.L. 2014-07 2014-03-08 /pmc/articles/PMC4119320/ /pubmed/24608209 http://dx.doi.org/10.4317/medoral.19399 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Yang, Wenli
Zhao, Sanjun
Liu, Fei
Sun, Minglei
Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap
title Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap
title_full Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap
title_fullStr Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap
title_full_unstemmed Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap
title_short Health-related quality of life after mandibular resection for oral cancer: Reconstruction with free fibula flap
title_sort health-related quality of life after mandibular resection for oral cancer: reconstruction with free fibula flap
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119320/
https://www.ncbi.nlm.nih.gov/pubmed/24608209
http://dx.doi.org/10.4317/medoral.19399
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