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Competing targets of microRNA-608 affect anxiety and hypertension

MicroRNAs (miRNAs) can repress multiple targets, but how a single de-balanced interaction affects others remained unclear. We found that changing a single miRNA–target interaction can simultaneously affect multiple other miRNA–target interactions and modify physiological phenotype. We show that miR-...

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Detalles Bibliográficos
Autores principales: Hanin, Geula, Shenhar-Tsarfaty, Shani, Yayon, Nadav, Hoe, Yau Yin, Bennett, Estelle R., Sklan, Ella H., Rao, Dabeeru. C., Rankinen, Tuomo, Bouchard, Claude, Geifman-Shochat, Susana, Shifman, Sagiv, Greenberg, David S., Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119407/
https://www.ncbi.nlm.nih.gov/pubmed/24722204
http://dx.doi.org/10.1093/hmg/ddu170