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Accumulation of small hyaluronan oligosaccharides in tumour interstitial fluid correlates with lymphatic invasion and lymph node metastasis

BACKGROUND: Association studies have implicated the glycosaminoglycan hyaluronan (hyaluronic acid, HA) and its degrading enzymes the hyaluronidases in tumour progression and metastasis. Oligosaccharides of degraded HA have been ascribed a number of biological functions that are not exerted by high-m...

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Detalles Bibliográficos
Autores principales:	Schmaus, A, Klusmeier, S, Rothley, M, Dimmler, A, Sipos, B, Faller, G, Thiele, W, Allgayer, H, Hohenberger, P, Post, S, Sleeman, J P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119989/ https://www.ncbi.nlm.nih.gov/pubmed/24937668 http://dx.doi.org/10.1038/bjc.2014.332

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