Methods for Predicting Diabetes Phase III Efficacy Outcome From Early Data: Superior Performance Obtained Using Longitudinal Approaches

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The link between glucose and HbA1c at steady state has previously been described using steady-state or longitudinal relationships. We evaluated five published methods for prediction of HbA1c after 26/28 weeks using data from four clinical trials. Methods (1) and (2): steady-state regression of HbA1c...

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Detalles Bibliográficos
Autores principales: Møller, J B, Kristensen, N R, Klim, S, Karlsson, M O, Ingwersen, S H, Kjellsson, M C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120014/
https://www.ncbi.nlm.nih.gov/pubmed/24988185
http://dx.doi.org/10.1038/psp.2014.20

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