Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability

While aspirin is generally effective for prevention of cardiovascular disease, considerable variation in drug response exists, resulting in some individuals displaying high on-treatment platelet reactivity. We used pharmacometabolomics to define pathways implicated in variation of response to treatm...

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Detalles Bibliográficos
Autores principales: Ellero-Simatos, S, Lewis, J P, Georgiades, A, Yerges-Armstrong, L M, Beitelshees, A L, Horenstein, R B, Dane, A, Harms, A C, Ramaker, R, Vreeken, R J, Perry, C G, Zhu, H, Sànchez, C L, Kuhn, C, Ortel, T L, Shuldiner, A R, Hankemeier, T, Kaddurah-Daouk, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120016/
https://www.ncbi.nlm.nih.gov/pubmed/25029353
http://dx.doi.org/10.1038/psp.2014.22

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