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Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements

Reverse transcription-derived sequences account for at least half of the human genome. Although these retroelements are formidable motors of evolution, they can occasionally cause disease, and accordingly are inactivated during early embryogenesis through epigenetic mechanisms. In the mouse, at leas...

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Detalles Bibliográficos
Autores principales: Turelli, Priscilla, Castro-Diaz, Nathaly, Marzetta, Flavia, Kapopoulou, Adamandia, Raclot, Charlène, Duc, Julien, Tieng, Vannary, Quenneville, Simon, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120080/
https://www.ncbi.nlm.nih.gov/pubmed/24879559
http://dx.doi.org/10.1101/gr.172833.114