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The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study

OBJECTIVE: Non-communicable diseases (NCDs) are the biggest cause of death in Europe putting an unsustainable burden on already struggling health systems. Increases in obesity are a major cause of NCDs. This paper projects the future burden of coronary heart disease (CHD), stroke, type 2 diabetes an...

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Autores principales: Webber, Laura, Divajeva, Diana, Marsh, Tim, McPherson, Klim, Brown, Martin, Galea, Gauden, Breda, Joao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120328/
https://www.ncbi.nlm.nih.gov/pubmed/25063459
http://dx.doi.org/10.1136/bmjopen-2014-004787
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author Webber, Laura
Divajeva, Diana
Marsh, Tim
McPherson, Klim
Brown, Martin
Galea, Gauden
Breda, Joao
author_facet Webber, Laura
Divajeva, Diana
Marsh, Tim
McPherson, Klim
Brown, Martin
Galea, Gauden
Breda, Joao
author_sort Webber, Laura
collection PubMed
description OBJECTIVE: Non-communicable diseases (NCDs) are the biggest cause of death in Europe putting an unsustainable burden on already struggling health systems. Increases in obesity are a major cause of NCDs. This paper projects the future burden of coronary heart disease (CHD), stroke, type 2 diabetes and seven cancers by 2030 in 53 WHO European Region countries based on current and past body mass index (BMI) trends. It also tests the impact of obesity interventions on the future disease burden. SETTING AND PARTICIPANTS: Secondary data analysis of country-specific epidemiological data using a microsimulation modelling process. INTERVENTIONS: The effect of three hypothetical scenarios on the future burden of disease in 2030 was tested: baseline scenario, BMI trends go unchecked; intervention 1, population BMI decreases by 1%; intervention 2, BMI decreases by 5%. PRIMARY AND SECONDARY OUTCOME MEASURES: Quantifying the future burden of major NCDs and the impact of interventions on this future disease burden. RESULTS: By 2030 in the whole of the European region, the prevalence of diabetes, CHD and stroke and cancers was projected to reach an average of 3990, 4672 and 2046 cases/100 000, respectively. The highest prevalence of diabetes was predicted in Slovakia (10 870), CHD and stroke—in Greece (11 292) and cancers—in Finland (5615 cases/100 000). A 5% fall in population BMI was projected to significantly reduce cumulative incidence of diseases. The largest reduction in diabetes and CHD and stroke was observed in Slovakia (3054 and 3369 cases/100 000, respectively), and in cancers was predicted in Germany (331/100 000). CONCLUSIONS: Modelling future disease trends is a useful tool for policymakers so that they can allocate resources effectively and implement policies to prevent NCDs. Future research will allow real policy interventions to be tested; however, better surveillance data on NCDs and their risk factors are essential for research and policy.
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spelling pubmed-41203282014-08-05 The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study Webber, Laura Divajeva, Diana Marsh, Tim McPherson, Klim Brown, Martin Galea, Gauden Breda, Joao BMJ Open Public Health OBJECTIVE: Non-communicable diseases (NCDs) are the biggest cause of death in Europe putting an unsustainable burden on already struggling health systems. Increases in obesity are a major cause of NCDs. This paper projects the future burden of coronary heart disease (CHD), stroke, type 2 diabetes and seven cancers by 2030 in 53 WHO European Region countries based on current and past body mass index (BMI) trends. It also tests the impact of obesity interventions on the future disease burden. SETTING AND PARTICIPANTS: Secondary data analysis of country-specific epidemiological data using a microsimulation modelling process. INTERVENTIONS: The effect of three hypothetical scenarios on the future burden of disease in 2030 was tested: baseline scenario, BMI trends go unchecked; intervention 1, population BMI decreases by 1%; intervention 2, BMI decreases by 5%. PRIMARY AND SECONDARY OUTCOME MEASURES: Quantifying the future burden of major NCDs and the impact of interventions on this future disease burden. RESULTS: By 2030 in the whole of the European region, the prevalence of diabetes, CHD and stroke and cancers was projected to reach an average of 3990, 4672 and 2046 cases/100 000, respectively. The highest prevalence of diabetes was predicted in Slovakia (10 870), CHD and stroke—in Greece (11 292) and cancers—in Finland (5615 cases/100 000). A 5% fall in population BMI was projected to significantly reduce cumulative incidence of diseases. The largest reduction in diabetes and CHD and stroke was observed in Slovakia (3054 and 3369 cases/100 000, respectively), and in cancers was predicted in Germany (331/100 000). CONCLUSIONS: Modelling future disease trends is a useful tool for policymakers so that they can allocate resources effectively and implement policies to prevent NCDs. Future research will allow real policy interventions to be tested; however, better surveillance data on NCDs and their risk factors are essential for research and policy. BMJ Publishing Group 2014-07-25 /pmc/articles/PMC4120328/ /pubmed/25063459 http://dx.doi.org/10.1136/bmjopen-2014-004787 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Public Health
Webber, Laura
Divajeva, Diana
Marsh, Tim
McPherson, Klim
Brown, Martin
Galea, Gauden
Breda, Joao
The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
title The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
title_full The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
title_fullStr The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
title_full_unstemmed The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
title_short The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
title_sort future burden of obesity-related diseases in the 53 who european-region countries and the impact of effective interventions: a modelling study
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120328/
https://www.ncbi.nlm.nih.gov/pubmed/25063459
http://dx.doi.org/10.1136/bmjopen-2014-004787
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