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Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia
INTRODUCTION: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. The long-term management of gout requires reduction of serum urate levels and this is most often achieved with use of xanthine oxidase inhibitors, such as allopurinol. Febuxos...
Autores principales: | MacDonald, Thomas M, Ford, Ian, Nuki, George, Mackenzie, Isla S, De Caterina, Raffaele, Findlay, Evelyn, Hallas, Jesper, Hawkey, Christopher J, Ralston, Stuart, Walters, Matthew, Webster, John, McMurray, John, Perez Ruiz, Fernando, Jennings, Claudine G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120410/ https://www.ncbi.nlm.nih.gov/pubmed/25011991 http://dx.doi.org/10.1136/bmjopen-2014-005354 |
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