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(4R)-3-Hy­droxy-7-isopropyl-4-methyl-5,6-di­hydro­benzo­furan-2(4H)-one

In the title compound, alternatively called α-hy­droxy-γ-alkyl­idenebutenolide, C(12)H(16)O(3), two independent mol­ecules (A and B) crystallize in the asymmetric unit in each of which the 5,6-di­hydro­benzo ring has an envelope conformation. The torsion angle along the butadiene chain in the γ-alky...

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Detalles Bibliográficos
Autores principales: Heinemann, Frank W., Herrera, Alberto, Agrifoglio, Giuseppe, Dorta, Romano, Pastrán, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120547/
https://www.ncbi.nlm.nih.gov/pubmed/25161599
http://dx.doi.org/10.1107/S1600536814014524
Descripción
Sumario:In the title compound, alternatively called α-hy­droxy-γ-alkyl­idenebutenolide, C(12)H(16)O(3), two independent mol­ecules (A and B) crystallize in the asymmetric unit in each of which the 5,6-di­hydro­benzo ring has an envelope conformation. The torsion angle along the butadiene chain in the γ-alkyl­idenebutenolide core is −177.9 (2)° for mol­ecule A and 179.9 (2)° for mol­ecule B. In the crystal, O—H⋯O hydrogen bonds between hy­droxyl and carbonyl groups of adjacent independent mol­ecules form dimers with R (2) (2)(10) loops.