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Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
The title compound, C(25)H(27)NO(4), has a flattened dihydropyridine ring. The benzene and phenyl rings are synclinal to one another, forming a dihedral angle of 49.82 (8)°; the axis of the biphenyl rings makes an 81.05 (9)° angle to the plane of the dihydropyridine ring. In the crystal, N—H⋯O h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120632/ https://www.ncbi.nlm.nih.gov/pubmed/25161575 http://dx.doi.org/10.1107/S1600536814013294 |
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author | Steiger, Scott A. Monacelli, Anthony J. Li, Chun Hunting, Janet L. Natale, Nicholas R. |
author_facet | Steiger, Scott A. Monacelli, Anthony J. Li, Chun Hunting, Janet L. Natale, Nicholas R. |
author_sort | Steiger, Scott A. |
collection | PubMed |
description | The title compound, C(25)H(27)NO(4), has a flattened dihydropyridine ring. The benzene and phenyl rings are synclinal to one another, forming a dihedral angle of 49.82 (8)°; the axis of the biphenyl rings makes an 81.05 (9)° angle to the plane of the dihydropyridine ring. In the crystal, N—H⋯O hydrogen bonds link the molecules into chain motifs running along the a-axis direction. The chains are cross-linked by C—H⋯O interactions, forming sheet motifs running slightly off the (110) plane, together with an intermolecular interaction between head-to tail biphenyl groups, thus making the whole crystal packing a three-dimensional network. Intramolecular C—H⋯O hydrogen bonds are also observed. |
format | Online Article Text |
id | pubmed-4120632 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-41206322014-08-26 Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Steiger, Scott A. Monacelli, Anthony J. Li, Chun Hunting, Janet L. Natale, Nicholas R. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(25)H(27)NO(4), has a flattened dihydropyridine ring. The benzene and phenyl rings are synclinal to one another, forming a dihedral angle of 49.82 (8)°; the axis of the biphenyl rings makes an 81.05 (9)° angle to the plane of the dihydropyridine ring. In the crystal, N—H⋯O hydrogen bonds link the molecules into chain motifs running along the a-axis direction. The chains are cross-linked by C—H⋯O interactions, forming sheet motifs running slightly off the (110) plane, together with an intermolecular interaction between head-to tail biphenyl groups, thus making the whole crystal packing a three-dimensional network. Intramolecular C—H⋯O hydrogen bonds are also observed. International Union of Crystallography 2014-06-18 /pmc/articles/PMC4120632/ /pubmed/25161575 http://dx.doi.org/10.1107/S1600536814013294 Text en © Steiger et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Steiger, Scott A. Monacelli, Anthony J. Li, Chun Hunting, Janet L. Natale, Nicholas R. Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title | Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_full | Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_fullStr | Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_full_unstemmed | Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_short | Diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_sort | diethyl 4-(biphenyl-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120632/ https://www.ncbi.nlm.nih.gov/pubmed/25161575 http://dx.doi.org/10.1107/S1600536814013294 |
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