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X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body

O-GlcNAc Transferase (OGT) catalyzes protein O-GlcNAcylation, an abundant and dynamic nuclear and cytosolic modification linked to epigenetic regulation of gene expression. The steady-state levels of O-GlcNAc are influenced by extracellular glucose concentrations suggesting that O-GlcNAcylation may...

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Detalles Bibliográficos
Autores principales:	Olivier-Van Stichelen, Stéphanie, Hanover, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120696/ https://www.ncbi.nlm.nih.gov/pubmed/25136351 http://dx.doi.org/10.3389/fgene.2014.00256

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