Induction of IL-12 Production in Human Peripheral Monocytes by Trypanosoma cruzi Is Mediated by Glycosylphosphatidylinositol-Anchored Mucin-Like Glycoproteins and Potentiated by IFN-γ and CD40-CD40L Interactions

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), is characterized by immunopathology driven by IFN-γ secreting Th1-like T cells. T. cruzi has a thick coat of mucin-like glycoproteins covering its surface, which plays an important role in parasite invasion and host immun...

Descripción completa

Detalles Bibliográficos
Autores principales: Abel, Lúcia Cristina Jamli, Ferreira, Ludmila Rodrigues Pinto, Cunha Navarro, Isabela, Baron, Monique Andrade, Kalil, Jorge, Gazzinelli, Ricardo Tostes, Rizzo, Luiz Vicente, Cunha-Neto, Edecio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120781/
https://www.ncbi.nlm.nih.gov/pubmed/25120285
http://dx.doi.org/10.1155/2014/345659

Ejemplares similares

Ejemplares similares