Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates

[Image: see text] A mild, practical protocol has been developed for the Suzuki cross-coupling of unprotected thienylsulfonamides from air- and bench-stable organotrifluoroborates in the absence of a protecting group on the sulfonamide nitrogen. The developed synthetic method can be applied to the pr...

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Autores principales: Noreen, Mnaza, Rasool, Nasir, El Khatib, Mirna, Molander, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120984/
https://www.ncbi.nlm.nih.gov/pubmed/25019222
http://dx.doi.org/10.1021/jo501323z
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author Noreen, Mnaza
Rasool, Nasir
El Khatib, Mirna
Molander, Gary A.
author_facet Noreen, Mnaza
Rasool, Nasir
El Khatib, Mirna
Molander, Gary A.
author_sort Noreen, Mnaza
collection PubMed
description [Image: see text] A mild, practical protocol has been developed for the Suzuki cross-coupling of unprotected thienylsulfonamides from air- and bench-stable organotrifluoroborates in the absence of a protecting group on the sulfonamide nitrogen. The developed synthetic method can be applied to the preparation of various arylated and heteroarylated thienylsulfonamides under conditions that are tolerant of a broad range of functional groups.
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spelling pubmed-41209842015-07-14 Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates Noreen, Mnaza Rasool, Nasir El Khatib, Mirna Molander, Gary A. J Org Chem [Image: see text] A mild, practical protocol has been developed for the Suzuki cross-coupling of unprotected thienylsulfonamides from air- and bench-stable organotrifluoroborates in the absence of a protecting group on the sulfonamide nitrogen. The developed synthetic method can be applied to the preparation of various arylated and heteroarylated thienylsulfonamides under conditions that are tolerant of a broad range of functional groups. American Chemical Society 2014-07-14 2014-08-01 /pmc/articles/PMC4120984/ /pubmed/25019222 http://dx.doi.org/10.1021/jo501323z Text en Copyright © 2014 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Noreen, Mnaza
Rasool, Nasir
El Khatib, Mirna
Molander, Gary A.
Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates
title Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates
title_full Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates
title_fullStr Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates
title_full_unstemmed Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates
title_short Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates
title_sort arylation and heteroarylation of thienylsulfonamides with organotrifluoroborates
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120984/
https://www.ncbi.nlm.nih.gov/pubmed/25019222
http://dx.doi.org/10.1021/jo501323z
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