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Mapping the Protein Interaction Landscape for Fully Functionalized Small-Molecule Probes in Human Cells
[Image: see text] Phenotypic screening provides a means to discover small molecules that perturb cell biological processes. Discerning the proteins and biochemical pathways targeted by screening hits, however, remains technically challenging. We recently described the use of small molecules bearing...
Autores principales: | Kambe, Tohru, Correia, Bruno E., Niphakis, Micah J., Cravatt, Benjamin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120992/ https://www.ncbi.nlm.nih.gov/pubmed/25045785 http://dx.doi.org/10.1021/ja505517t |
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